Chemistry of active enzymes and free radicals and organism. 4. Active oxygen, free radicals and diseases.

Biochemistry of Oxygen and Its Free Radicals

Thrombolytic treatment in acute myocardial infarction achieves coronary patency in most patients.' Mortality in groups treated early after the onset of symptoms is significantly reduced,' but left ventricular function does not always improve.5 Myocardial necrosis during the period of vessel occlusion is partly responsible for the irreversible ventricular impairment that occurs even when the ves...

Oxygen free radicals and retinopathy of prematurity.

Oxygen free radicals and congestive heart failure.

Plasma lipid peroxides (malondialdehyde) and thiols were measured in 45 patients with congestive heart failure and 45 controls. Malondialdehyde concentrations were significantly higher in the patients with congestive heart failure (median 9.0 nmol/ml interquartile range (IQR) 7.9-10.2) than in the controls (median 7.7 nmol/ml (IQR 6.9-9.2)). Plasma thiols were significantly lower in congestive ...

Free Radicals and Cardiovascular Diseases: An Update

Sanjib Bhattacharya, KK Mueen Ahmed, Subhankar Chakraborty 1 Bengal School of Technology (A College of Pharmacy), Delhi Road, Sugandha, Hooghly 712102, West Bengal, India. 2 Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Hassa, Saudi Arabia. 3 Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center Omaha, NE68198-5...

Free Radicals in Cardiovascular Diseases

During the past several years, there has been a growing interest in the medical implications of free radicals. These chemical entities are common by-products of many oxidative biochemical reactions in the cell. Free radicals are essential to a number of normal biochemical and physiological processes. They are too reactive to be tolerated in living tissue, and aerobic organisms use sophisticated...